It has been 49 years since the last discovery of a new virus family in the model yeast Saccharomyces cerevisiae.A large-scale screen to determine the diversity of double-stranded RNA (dsRNA) viruses in S.cerevisiae has identified multiple novel viruses from the family Partitiviridae that have been previously shown to infect plants, fungi, protozoan
The hyperinflammation microenvironment after spinal cord injury (SCI) remains a great challenge for neural regeneration.Methylprednisolone has been used to reduce the inflammatory response after SCI, but it is controversial due to side effects associated with off-specific targeting effects.In this study, we synthesized in situ 5-ASA grafted chitosa
The origin of life involved complicated evolutionary processes.Computer modeling is a promising way to reveal relevant mechanisms.However, due to the limitation of our knowledge on prebiotic chemistry, it is usually difficult to justify parameter-setting for the modeling.Thus, typically, the studies were conducted in a reverse way: the parameter-sp
Endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction is a common and preferred choice for gallstone disease.Laparoscopic common bile duct exploration (LCBDE) and laparoscopic cholecystectomy (LC) are being increasingly used for managing choledocholithiasis and cholecystolithiasis.We report a case of a Hem-o-lok clip that was
When faced with rapidly changing environments, wildlife species are left to adapt, disperse or disappear.Consequently, there is value in investigating the connectivity of populations of species inhabiting different environments in order to evaluate dispersal as a potential strategy for persistence in the face of climate change.Here, we begin to inv